Homeopathic potencies of Opium in alcohol dependence: exploratory open-label study

Authors

  • Ubiratan Cardinalli Adler Universidade Federal de São Paulo
  • Ana Elisa Madureira Padula Universidade Federal São Paulo
  • Amarilys de Toledo Cesar Universidade Federal São Paulo
  • Maristela Schiabel Adler Departamento de Psicobiologia
  • José Carlos Fernandes Galduróz Universidade Federal de São Paulo

DOI:

https://doi.org/10.51910/ijhdr.v11i38.548

Keywords:

alcohol dependence, homeopathy

Abstract

Background: The conventional pharmacological options for the treatment of alcoholism are limited, which led to the search for solutions in alternative or complementary medicine (CAM). Homeopathy is a CAM modality recognized as medical specialty in Brazil. According to the clinical experience of the early homeopaths, Opium was used to treat patients with alcohol dependence. Aim: to perform a preliminary assessment of the effectiveness and tolerability of fifty-millesimal potencies of Opium in the treatment of alcohol-dependent patients. Methods: exploratory, prospective, open-label trial, with pre-treatment measures as control. Confidence intervals were used to estimate the magnitude of the clinical differences. Results: a total of 14 patients were included, from which 12 were evaluated (intention to treat analysis - ITT). There was a significant reduction in the average daily alcohol consumption (-29.37 units of alcohol/day; 95% CI=10.63; 48.11) and in the severity of alcohol dependence, measured by the mean score of the Short Alcohol Dependence Data questionnaire (-10.17; 95% CI= 4.12; 16.22). No serious adverse events were reported. Randomized controlled studies with larger samples are needed.

Author Biographies

Ubiratan Cardinalli Adler, Universidade Federal de São Paulo

Departamento de Psicobiologia Pesquisador associado

Ana Elisa Madureira Padula, Universidade Federal São Paulo

Departamento de Psicobiologia Pesquisador associado

Amarilys de Toledo Cesar, Universidade Federal São Paulo

Departamento de Psicobiologia Pesquisador associado

Maristela Schiabel Adler, Departamento de Psicobiologia

Departamento de Psicobiologia Pesquisador associado

José Carlos Fernandes Galduróz, Universidade Federal de São Paulo

Departamento de Psicobiologia Professor Adjunto

Downloads

Published

2021-12-21

How to Cite

Adler, U. C., Padula, A. E. M., Cesar, A. de T., Adler, M. S., & Galduróz, J. C. F. (2021). Homeopathic potencies of Opium in alcohol dependence: exploratory open-label study. International Journal of High Dilution Research - ISSN 1982-6206, 11(38), 19–24. https://doi.org/10.51910/ijhdr.v11i38.548

Issue

Section

Clinical Research

Most read articles by the same author(s)