Effect of Zincum metallicum and LPS treatments on femoral bone density in pregnant mice
DOI:
https://doi.org/10.51910/ijhdr.v14i2.798Keywords:
perinatal, BALB/C, mice, Zincum metallicum, LPS, bone, femur, density, dimorphismAbstract
Background: The simulated bacterial infection is a classical experimental model, by the injection of purified gram negative bacteria wall lipopolysaccharide (LPS) which produces effects similar to real infection, but without presence of the microorganism. The LPS is a stress factor as during the pregnancy and delivery, and pilot experiments have shown that ultra-high dilutions (UHD) may have a beneficial role in reducing the LPS stress. Zincum metallicum (Zm) has a potential to influence several physiological aspects of a living organism. It was chosen by a team of researchers from GIRI, to explore the effect of Zm on various experimental model (Zincum project). The optical density is a radiographic method for the measurement of the amount of hard bone tissue, and is an accessible, simple and non-invasive method. It is hypothesized that UHD Zm may influence the Zinc metabolism, therefore, bone tissues were collected to evaluate the zinc concentration.Downloads
Published
2021-08-27
How to Cite
da Silva, S. L. M., Correa, M. D., Costa, C., Pecorari, V. G. A., Arita, E. S., Bernardi, M. M., Holandino, C., & Bonamin, L. V. (2021). Effect of Zincum metallicum and LPS treatments on femoral bone density in pregnant mice. International Journal of High Dilution Research - ISSN 1982-6206, 14(2), 35–39. https://doi.org/10.51910/ijhdr.v14i2.798
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Copyright (c) 2015 Silvio Leite Monteiro da Silva, Maristela Dutra Correa, Claudio Costa, Vanessa Gallego Arias Pecorari, Emiko Saito Arita, Maria Martha Bernardi, Carla Holandino, Leoni Villano Bonamin
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